Version 5.4
Bos taurus Gene: ARSG
Summary
InnateDB Gene IDBG-643699.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARSG
Gene Name arylsulfatase G
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010637
Encoded Proteins
IDBP-696277
arylsulfatase G
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000141337:
The protein encoded by this gene belongs to the sulfatase enzyme family. Sulfatases hydrolyze sulfate esters from sulfated steroids, carbohydrates, proteoglycans, and glycolipids. They are involved in hormone biosynthesis, modulation of cell signaling, and degradation of macromolecules. This protein displays arylsulfatase activity at acidic pH, as is typical of lysosomal sulfatases, and has been shown to localize in the lysosomes. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jun 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:62368464-62401915
Strand Forward strand
Band
Transcripts
ENSBTAT00000014061 ENSBTAP00000014061
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0008484 sulfuric ester hydrolase activity
Biological Process
GO:0006790 sulfur compound metabolic process
GO:0008152 metabolic process
Cellular Component
GO:0005615 extracellular space
GO:0005764 lysosome
GO:0005783 endoplasmic reticulum
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000141337
View Gene Order
ENSMUSG00000020604
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_121036
The activation of arylsulfatases pathway
REACT_116105
Glycosphingolipid metabolism pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_22161
Post-translational protein modification pathway
REACT_1069
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
REACT_17015
Metabolism of proteins pathway
REACT_111217
Metabolism pathway
REACT_198990
The activation of arylsulfatases pathway
REACT_199008
Glycosphingolipid metabolism pathway
REACT_188937
Metabolism pathway
REACT_245163
Sphingolipid metabolism pathway
REACT_247926
Metabolism of proteins pathway
REACT_236283
Post-translational protein modification pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_229541
PTM: gamma carboxylation, hypusine formation and arylsulfatase activation pathway
KEGG
hsa04142
Lysosome pathway
mmu04142
Lysosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.103824
RefSeq NM_001101967
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca