InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CHRM1

Summary

InnateDB Gene

IDBG-643720.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CHRM1

Gene Name

muscarinic acetylcholine receptor M1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000011579

Encoded Proteins

IDBP-696295

cholinergic receptor, muscarinic 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000168539:
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 29:41919874-41921707

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000015383

ENSBTAP00000047523

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0016907	G-protein coupled acetylcholine receptor activity

Biological Process

GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
GO:0040012	regulation of locomotion
GO:0043270	positive regulation of ion transport
GO:0046541	saliva secretion
GO:0050890	cognition