Version 5.4
Bos taurus Gene: LRRC6
Summary
InnateDB Gene IDBG-644094.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRRC6
Gene Name Protein TILB homolog
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010548
Encoded Proteins
IDBP-696705
leucine-rich repeat-containing protein 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000129295:
The protein encoded by this gene contains several leucine-rich repeat domains and appears to be involved in the motility of cilia. Defects in this gene are a cause of primary ciliary dyskinesia-19 (CILD19). Two transcript variants, one protein-coding and the other not, have been found for this gene. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:9657203-9728203
Strand Forward strand
Band
Transcripts
ENSBTAT00000048498 ENSBTAP00000045522
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0003341 cilium movement
GO:0008584 male gonad development
GO:0030317 sperm motility
GO:0036158 outer dynein arm assembly
GO:0036159 inner dynein arm assembly
GO:0044458 motile cilium assembly
GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry
GO:0061458 reproductive system development
Cellular Component
GO:0005737 cytoplasm
GO:0005929 cilium
GO:0042995 cell projection
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000129295
View Gene Order
ENSMUSG00000022375
View Gene Order
Cross-References
SwissProt Q1RMR5
TrEMBL
UniProt Splice Variant
Entrez Gene 527979
UniGene Bt.39868
RefSeq NM_001075904 XM_005215336
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114759 DAAA02037595
GenPept AAI14760
RNA Seq Atlas 527979

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca