Version 5.4
Bos taurus Protein: LRRC6
Summary
InnateDB Protein IDBP-696705.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LRRC6
Protein Name leucine-rich repeat-containing protein 6
Synonyms
Species Bos taurus
Ensembl Protein ENSBTAP00000045522
InnateDB Gene IDBG-644094 (LRRC6)
Protein Structure
UniProt Annotation
Function May play a role in dynein arm assembly, hence essential for proper axoneme building for cilia motility. {ECO:0000250}.
Subcellular Localization Cytoplasm {ECO:0000250}. Cell projection, cilium {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0003341 cilium movement
GO:0008584 male gonad development
GO:0030317 sperm motility
GO:0036158 outer dynein arm assembly
GO:0036159 inner dynein arm assembly
GO:0044458 motile cilium assembly
GO:0060287 epithelial cilium movement involved in determination of left/right asymmetry
GO:0061458 reproductive system development
Cellular Component
GO:0005737 cytoplasm
GO:0005929 cilium
GO:0042995 cell projection
Protein Structure and Domains
PDB ID
InterPro IPR003603 U2A\'/phosphoprotein 32 family A, C-terminal
PFAM
PRINTS
PIRSF
SMART SM00446
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q1RMR5
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 527979
UniGene Bt.39868
RefSeq NP_001069372
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114759 DAAA02037595
GenPept AAI14760

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca