Bos taurus Gene: GNA11 | |||||||||||||||||||||||
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Summary | |||||||||||||||||||||||
InnateDB Gene | IDBG-644445.3 | ||||||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||||||
Gene Symbol | GNA11 | ||||||||||||||||||||||
Gene Name | Guanine nucleotide-binding protein subunit alpha-11 | ||||||||||||||||||||||
Synonyms | |||||||||||||||||||||||
Species | Bos taurus | ||||||||||||||||||||||
Ensembl Gene | ENSBTAG00000012181 | ||||||||||||||||||||||
Encoded Proteins |
Guanine nucleotide-binding protein subunit alpha-11
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Protein Structure | |||||||||||||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000088256:
The protein encoded by this gene belongs to the family of guanine nucleotide-binding proteins (G proteins), which function as modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes one of the alpha subunits (subunit alpha-11). Mutations in this gene have been associated with hypocalciuric hypercalcemia type II (HHC2) and hypocalcemia dominant 2 (HYPOC2). Patients with HHC2 and HYPOC2 exhibit decreased or increased sensitivity, respectively, to changes in extracellular calcium concentrations. [provided by RefSeq, Dec 2013] |
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Gene Information | |||||||||||||||||||||||
Type | Protein coding | ||||||||||||||||||||||
Genomic Location | Chromosome 7:21937788-21953374 | ||||||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||||||
Band | |||||||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathways | |||||||||||||||||||||||
NETPATH | |||||||||||||||||||||||
REACTOME |
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion pathway
Platelet sensitization by LDL pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Regulation of insulin secretion pathway
Signaling by GPCR pathway
Free fatty acids regulate insulin secretion pathway
Hemostasis pathway
Integration of energy metabolism pathway
Platelet activation, signaling and aggregation pathway
Signal Transduction pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
Signal amplification pathway
G-protein mediated events pathway
Platelet homeostasis pathway
ADP signalling through P2Y purinoceptor 1 pathway
G alpha (q) signalling events pathway
GPCR downstream signaling pathway
PLC beta mediated events pathway
Thromboxane signalling through TP receptor pathway
Metabolism pathway
Opioid Signalling pathway
Acetylcholine regulates insulin secretion pathway
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KEGG | |||||||||||||||||||||||
INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Pathway Predictions based on Human Orthology Data | |||||||||||||||||||||||
NETPATH |
TSH pathway
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REACTOME |
ADP signalling through P2Y purinoceptor 1 pathway
Thromboxane signalling through TP receptor pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Acetylcholine regulates insulin secretion pathway
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion pathway
Regulation of insulin secretion pathway
Integration of energy metabolism pathway
Signaling by GPCR pathway
Platelet activation, signaling and aggregation pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Free fatty acids regulate insulin secretion pathway
Metabolism pathway
Signal amplification pathway
Hemostasis pathway
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion pathway
GPCR downstream signaling pathway
Platelet homeostasis pathway
Hemostasis pathway
Thromboxane signalling through TP receptor pathway
Signaling by GPCR pathway
Integration of energy metabolism pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Acetylcholine regulates insulin secretion pathway
Metabolism pathway
Platelet activation, signaling and aggregation pathway
Regulation of insulin secretion pathway
Platelet sensitization by LDL pathway
Thrombin signalling through proteinase activated receptors (PARs) pathway
ADP signalling through P2Y purinoceptor 1 pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
Free fatty acids regulate insulin secretion pathway
Signal amplification pathway
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KEGG |
GnRH signaling pathway pathway
Gap junction pathway
Long-term depression pathway
Calcium signaling pathway pathway
Vascular smooth muscle contraction pathway
Amoebiasis pathway
Chagas disease (American trypanosomiasis) pathway
Calcium signaling pathway pathway
Gap junction pathway
GnRH signaling pathway pathway
Long-term depression pathway
Vascular smooth muscle contraction pathway
Amoebiasis pathway
Chagas disease (American trypanosomiasis) pathway
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INOH | |||||||||||||||||||||||
PID NCI | |||||||||||||||||||||||
Cross-References | |||||||||||||||||||||||
SwissProt | |||||||||||||||||||||||
TrEMBL | |||||||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||||||
Entrez Gene | |||||||||||||||||||||||
UniGene | Bt.5511 | ||||||||||||||||||||||
RefSeq | NM_174322 | ||||||||||||||||||||||
HUGO | |||||||||||||||||||||||
OMIM | |||||||||||||||||||||||
CCDS | |||||||||||||||||||||||
HPRD | |||||||||||||||||||||||
IMGT | |||||||||||||||||||||||
EMBL | |||||||||||||||||||||||
GenPept | |||||||||||||||||||||||
RNA Seq Atlas | |||||||||||||||||||||||