InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: ABHD5

Summary

InnateDB Gene

IDBG-644476.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ABHD5

Gene Name

1-acylglycerol-3-phosphate O-acyltransferase ABHD5

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000008416

Encoded Proteins

IDBP-697118

1-acylglycerol-3-phosphate O-acyltransferase ABHD5

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000011198:
The protein encoded by this gene belongs to a large family of proteins defined by an alpha/beta hydrolase fold, and contains three sequence motifs that correspond to a catalytic triad found in the esterase/lipase/thioesterase subfamily. It differs from other members of this subfamily in that its putative catalytic triad contains an asparagine instead of the serine residue. Mutations in this gene have been associated with Chanarin-Dorfman syndrome, a triglyceride storage disease with impaired long-chain fatty acid oxidation. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 22:14451242-14492710

Strand

Forward strand

Band

Transcripts

ENSBTAT00000030667

ENSBTAP00000030639

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0016787	hydrolase activity
GO:0042171	lysophosphatidic acid acyltransferase activity

Biological Process

GO:0006654	phosphatidic acid biosynthetic process
GO:0010891	negative regulation of sequestering of triglyceride
GO:0010898	positive regulation of triglyceride catabolic process
GO:0051006	positive regulation of lipoprotein lipase activity