Version 5.4
Bos taurus Gene: C22H3ORF10
Summary
InnateDB Gene IDBG-644625.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol C22H3ORF10
Gene Name probable protein BRICK1
Synonyms C22H3orf10
Species Bos taurus
Ensembl Gene ENSBTAG00000016098
Encoded Proteins
IDBP-697273
probable protein BRICK1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000254999:
Gene Information
Type Protein coding
Genomic Location Chromosome 22:16769773-16777323
Strand Reverse strand
Band
Transcripts
ENSBTAT00000021429 ENSBTAP00000021429
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0032403 protein complex binding
GO:0048365 Rac GTPase binding
Biological Process
GO:0001701 in utero embryonic development
GO:0008284 positive regulation of cell proliferation
GO:0010592 positive regulation of lamellipodium assembly
GO:0016601 Rac protein signal transduction
GO:0030036 actin cytoskeleton organization
GO:0048870 cell motility
GO:0070207 protein homotrimerization
GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation
Cellular Component
GO:0030027 lamellipodium
GO:0031209 SCAR complex
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Homo sapiens
Gene ID
Gene Order
ENSMUSG00000033940
View Gene Order
ENSG00000254999
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_239142
Innate Immune System pathway
REACT_198374
Regulation of actin dynamics for phagocytic cup formation pathway
REACT_227951
Signaling by VEGF pathway
REACT_230745
Immune System pathway
REACT_257088
VEGFA-VEGFR2 Pathway pathway
REACT_209368
Fcgamma receptor (FCGR) dependent phagocytosis pathway
REACT_188257
Signal Transduction pathway
REACT_160086
Regulation of actin dynamics for phagocytic cup formation pathway
REACT_12529
Signaling by VEGF pathway
REACT_6802
Innate Immune System pathway
REACT_111102
Signal Transduction pathway
REACT_6900
Immune System pathway
REACT_228166
VEGFA-VEGFR2 Pathway pathway
REACT_160123
Fcgamma receptor (FCGR) dependent phagocytosis pathway
KEGG
mmu04810
Regulation of actin cytoskeleton pathway
hsa04810
Regulation of actin cytoskeleton pathway
INOH
PID NCI
erbb1_downstream_pathway
ErbB1 downstream signaling
rac1_pathway
RAC1 signaling pathway
pdgfrbpathway
PDGFR-beta signaling pathway
Cross-References
SwissProt
TrEMBL A8YXX8
UniProt Splice Variant
Entrez Gene 540092
UniGene Bt.37897
RefSeq NM_001114510
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102222 DAAA02053753
GenPept AAI02223
RNA Seq Atlas 540092

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca