Version 5.4
Bos taurus Gene: KHDRBS1
Summary
InnateDB Gene IDBG-644639.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KHDRBS1
Gene Name KH domain-containing, RNA-binding, signal transduction-associated protein 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012497
Encoded Proteins
IDBP-697288
KH domain-containing, RNA-binding, signal transduction-associated protein 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121774:
This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
This gene encodes a member of the K homology domain-containing, RNA-binding, signal transduction-associated protein family. The encoded protein appears to have many functions and may be involved in a variety of cellular processes, including alternative splicing, cell cycle regulation, RNA 3\'-end formation, tumorigenesis, and regulation of human immunodeficiency virus gene expression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:122233943-122257545
Strand Reverse strand
Band
Transcripts
ENSBTAT00000016581 ENSBTAP00000016581
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 124 interaction(s) predicted by orthology.
Predicted by orthology
Total 124 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0005070 SH3/SH2 adaptor activity
GO:0005515 protein binding
GO:0008143 poly(A) binding
GO:0008266 poly(U) RNA binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0009967 positive regulation of signal transduction
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045948 positive regulation of translational initiation
GO:0046831 regulation of RNA export from nucleus
GO:0046833 positive regulation of RNA export from nucleus
Cellular Component
GO:0005634 nucleus
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000121774
View Gene Order
ENSMUSG00000028790
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_4
EGFR1 pathway
NetPath_11
TCR pathway
NetPath_22
Leptin pathway
NetPath_56
Prolactin pathway
REACTOME
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q29RQ2
UniProt Splice Variant
Entrez Gene 538775
UniGene Bt.23430
RefSeq NM_001046442
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114075 DAAA02006245
GenPept AAI14076
RNA Seq Atlas 538775

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca