Bos taurus Gene: MSC
Summary
InnateDB Gene IDBG-644727.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MSC
Gene Name musculin
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000005404
Encoded Proteins
musculin
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178860:
The protein encoded by this gene is a transcriptional repressor capable of binding an E-box element either as a homodimer or as a heterodimer with E2A in vitro. The encoded protein also forms heterodimers with E2A proteins in vivo. This protein is capable of inhibiting the transactivation capability of E47, an E2A protein, in mammalian cells. This gene is a downstream target of the B-cell receptor signal transduction pathway. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:37549339-37551351
Strand Reverse strand
Band
Transcripts
ENSBTAT00000046864 ENSBTAP00000044112
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001206 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0046983 protein dimerization activity
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0014707 branchiomeric skeletal muscle development
GO:0060021 palate development
GO:0060539 diaphragm development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL G3X7V5
UniProt Splice Variant
Entrez Gene 507407
UniGene
RefSeq NM_001192146
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02038813
GenPept
RNA Seq Atlas 507407