Bos taurus Gene: FABP4
Summary
InnateDB Gene IDBG-644862.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FABP4
Gene Name fatty acid-binding protein, adipocyte
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000037526
Encoded Proteins
fatty acid-binding protein, adipocyte
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170323:
FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]
FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:46833665-46838053
Strand Reverse strand
Band
Transcripts
ENSBTAT00000000079 ENSBTAP00000000079
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005215 transporter activity
GO:0008289 lipid binding
Biological Process
GO:0001816 cytokine production
GO:0006469 negative regulation of protein kinase activity
GO:0006810 transport
GO:0042632 cholesterol homeostasis
GO:0045892 negative regulation of transcription, DNA-templated
GO:0050729 positive regulation of inflammatory response
GO:0050872 white fat cell differentiation
GO:0050873 brown fat cell differentiation
GO:0071285 cellular response to lithium ion
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis pathway
Transcriptional regulation of white adipocyte differentiation pathway
Developmental Biology pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Lipid digestion, mobilization, and transport pathway
Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes pathway
Transcriptional regulation of white adipocyte differentiation pathway
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis pathway
Mus musculus biological processes pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Lipid digestion, mobilization, and transport pathway
Developmental Biology pathway
KEGG
PPAR signaling pathway pathway
PPAR signaling pathway pathway
INOH
PID NCI
AP-1 transcription factor network
Cross-References
SwissProt
TrEMBL F1MHQ4
UniProt Splice Variant
Entrez Gene 281759
UniGene Bt.97
RefSeq NM_174314
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02039030
GenPept
RNA Seq Atlas 281759