InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Fabp4

Summary

InnateDB Gene

IDBG-131207.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Fabp4

Gene Name

fatty acid binding protein 4, adipocyte

Synonyms

422/aP2; ALBP/Ap2; Ap2; Lbpl

Species

Mus musculus

Ensembl Gene

ENSMUSG00000062515

Encoded Proteins

IDBP-131209

fatty acid binding protein 4, adipocyte

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170323:
FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]
FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:10204347-10208576

Strand

Reverse strand

Band

Transcripts

ENSMUST00000029041

ENSMUSP00000029041

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.

Experimentally validated
Total	5 [view]
Protein-Protein	3 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	9 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005215	transporter activity
GO:0008289	lipid binding

Biological Process

GO:0001816	cytokine production
GO:0006469	negative regulation of protein kinase activity
GO:0006810	transport
GO:0042632	cholesterol homeostasis
GO:0045892	negative regulation of transcription, DNA-templated
GO:0050729	positive regulation of inflammatory response
GO:0050872	white fat cell differentiation
GO:0050873	brown fat cell differentiation
GO:0071285	cellular response to lithium ion