Bos taurus Gene: MED18
Summary
InnateDB Gene IDBG-644890.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MED18
Gene Name Mediator of RNA polymerase II transcription subunit 18
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002678
Encoded Proteins
Mediator of RNA polymerase II transcription subunit 18
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130772:
MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:125653307-125658882
Strand Reverse strand
Band
Transcripts
ENSBTAT00000003468 ENSBTAP00000003468
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.
Predicted by orthology
Total 43 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001104 RNA polymerase II transcription cofactor activity
GO:0005515 protein binding
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
GO:0016592 mediator complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Transcriptional regulation of white adipocyte differentiation pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
PPARA activates gene expression pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Developmental Biology pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
PPARA activates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Transcriptional regulation of white adipocyte differentiation pathway
Developmental Biology pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes pathway
Transcriptional regulation of white adipocyte differentiation pathway
Mus musculus biological processes pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
PPARA activates gene expression pathway
Developmental Biology pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q0VCD4
TrEMBL
UniProt Splice Variant
Entrez Gene 540695
UniGene Bt.27848
RefSeq NM_001076235 XM_005203228
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120223
GenPept AAI20224
RNA Seq Atlas 540695