InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Med18

Summary

InnateDB Gene

IDBG-194008.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Med18

Gene Name

mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)

Synonyms

2810046C01Rik

Species

Mus musculus

Ensembl Gene

ENSMUSG00000066042

Encoded Proteins

IDBP-194010

mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)

IDBP-535076

mediator of RNA polymerase II transcription, subunit 18 homolog (yeast)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000130772:
MED18 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II (Sato et al., 2003 [PubMed 12584197]).[supplied by OMIM, Oct 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 4:132458731-132463921

Strand

Reverse strand

Band

D2.3

Transcripts

ENSMUST00000102567	ENSMUSP00000099627
ENSMUST00000123604	ENSMUSP00000120535

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	43 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001104	RNA polymerase II transcription cofactor activity
GO:0005515	protein binding

Biological Process

GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter
GO:0008150	biological_process