Bos taurus Gene: TRHR
Summary
InnateDB Gene IDBG-644938.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TRHR
Gene Name Thyrotropin-releasing hormone receptor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019997
Encoded Proteins
Thyrotropin-releasing hormone receptor
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000174417:
This gene encodes a G protein-coupled receptor for thyrotropin-releasing hormone (TRH). Upon binding to TRH, this receptor activates the inositol phospholipid-calcium-protein kinase C transduction pathway. Mutations in this gene have been associated with generalized thyrotropin-releasing hormone resistance. [provided by RefSeq, Sep 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:57479102-57524004
Strand Reverse strand
Band
Transcripts
ENSBTAT00000026634 ENSBTAP00000026634
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
GO:0004930 G-protein coupled receptor activity
GO:0004997 thyrotropin-releasing hormone receptor activity
Biological Process
GO:0007165 signal transduction
GO:0007186 G-protein coupled receptor signaling pathway
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Peptide ligand-binding receptors pathway
Signaling by GPCR pathway
Signal Transduction pathway
G alpha (q) signalling events pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
Class A/1 (Rhodopsin-like receptors) pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Peptide ligand-binding receptors pathway
Class A/1 (Rhodopsin-like receptors) pathway
Signaling by GPCR pathway
Signal Transduction pathway
GPCR downstream signaling pathway
GPCR ligand binding pathway
GPCR downstream signaling pathway
Signaling by GPCR pathway
Class A/1 (Rhodopsin-like receptors) pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
GPCR ligand binding pathway
Peptide ligand-binding receptors pathway
G alpha (q) signalling events pathway
Signal Transduction pathway
KEGG
Neuroactive ligand-receptor interaction pathway
Calcium signaling pathway pathway
Calcium signaling pathway pathway
Neuroactive ligand-receptor interaction pathway
INOH
PID NCI
Cross-References
SwissProt O46639
TrEMBL
UniProt Splice Variant
Entrez Gene 281549
UniGene Bt.45042
RefSeq NM_174203
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL D83964
GenPept BAA24069
RNA Seq Atlas 281549