Version 5.4
Bos taurus Gene: BT.17618
Summary
InnateDB Gene IDBG-645000.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.17618
Gene Name geranylgeranyl transferase type-1 subunit beta
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001895
Encoded Proteins
IDBP-697680
geranylgeranyl transferase type-1 subunit beta
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164219:
Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]
Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which \'A\' is an aliphatic amino acid and \'X\' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:3997971-4051209
Strand Reverse strand
Band
Transcripts
ENSBTAT00000002466 ENSBTAP00000002466
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004661 protein geranylgeranyltransferase activity
Biological Process
GO:0008152 metabolic process
GO:0018344 protein geranylgeranylation
Cellular Component
GO:0005953 CAAX-protein geranylgeranyltransferase complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000164219
View Gene Order
ENSMUSG00000024477
View Gene Order
Cross-References
SwissProt
TrEMBL F1N4H5
UniProt Splice Variant
Entrez Gene 509322
UniGene
RefSeq NM_001015560
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02027677 DAAA02027678 DAAA02027679 DAAA02027680
GenPept
RNA Seq Atlas 509322

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca