Version 5.4
Bos taurus Gene: OSBPL5
Summary
InnateDB Gene IDBG-645118.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OSBPL5
Gene Name Oxysterol-binding protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000001077
Encoded Proteins
IDBP-697811
oxysterol binding protein-like 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000021762:
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 29:49122352-49157383
Strand Forward strand
Band
Transcripts
ENSBTAT00000044244 ENSBTAP00000041753
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015485 cholesterol binding
Biological Process
GO:0006810 transport
GO:0006869 lipid transport
Cellular Component
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000021762
View Gene Order
ENSMUSG00000037606
View Gene Order
Cross-References
SwissProt
TrEMBL E1BC89
UniProt Splice Variant
Entrez Gene 532690
UniGene Bt.5374
RefSeq XM_002699428 XM_005227388 XM_005227389 XM_005227390 XM_869903
HUGO HGNC:16392
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02063699 DAAA02063700 DAAA02063701
GenPept
RNA Seq Atlas 532690

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca