Homo sapiens Gene: OSBPL5
Summary
InnateDB Gene IDBG-23966.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OSBPL5
Gene Name oxysterol binding protein-like 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000021762
Encoded Proteins
oxysterol binding protein-like 5
oxysterol binding protein-like 5
oxysterol binding protein-like 5
oxysterol binding protein-like 5
oxysterol binding protein-like 5
oxysterol binding protein-like 5
oxysterol binding protein-like 5
oxysterol binding protein-like 5
oxysterol binding protein-like 5
oxysterol binding protein-like 5
oxysterol binding protein-like 5
oxysterol binding protein-like 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors that play a key role in the maintenance of cholesterol balance in the body. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. This gene has been shown to be imprinted, with preferential expression from the maternal allele only in placenta. Transcript variants encoding different isoforms have been identified. [provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:3087116-3166739
Strand Reverse strand
Band p15.4
Transcripts
ENST00000263650 ENSP00000263650
ENST00000348039 ENSP00000302872
ENST00000389989 ENSP00000374639
ENST00000478260 ENSP00000437141
ENST00000471998 ENSP00000434265
ENST00000498536
ENST00000459995
ENST00000465323
ENST00000477622
ENST00000534454 ENSP00000431412
ENST00000525498 ENSP00000433342
ENST00000534491
ENST00000532951
ENST00000533234 ENSP00000436950
ENST00000526122 ENSP00000433754
ENST00000530372 ENSP00000435812
ENST00000533721 ENSP00000432507
ENST00000534157 ENSP00000433222
ENST00000528124
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008142 oxysterol binding
GO:0015485 cholesterol binding
Biological Process
GO:0006869 lipid transport
GO:0006893 Golgi to plasma membrane transport
GO:0008203 cholesterol metabolic process
GO:0030301 cholesterol transport
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.436166
RefSeq NM_001144063 NM_020896 NM_145638
HUGO
OMIM
CCDS CCDS31343 CCDS31344
HPRD 09475
IMGT
EMBL
GenPept
RNA Seq Atlas