InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: INS

Summary

InnateDB Gene

IDBG-645238.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

INS

Gene Name

insulin preproprotein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000013003

Encoded Proteins

IDBP-697932

insulin precursor

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 29:50036101-50037262

Strand

Forward strand

Band

Transcripts

ENSBTAT00000017289

ENSBTAP00000017289

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0005158	insulin receptor binding
GO:0005159	insulin-like growth factor receptor binding
GO:0005179	hormone activity
GO:0005515	protein binding
GO:0042802	identical protein binding

Biological Process

GO:0000165	MAPK cascade
GO:0002674	negative regulation of acute inflammatory response
GO:0005975	carbohydrate metabolic process
GO:0006006	glucose metabolic process
GO:0006521	regulation of cellular amino acid metabolic process
GO:0006953	acute-phase response
GO:0007186	G-protein coupled receptor signaling pathway
GO:0008284	positive regulation of cell proliferation
GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling
GO:0015758	glucose transport
GO:0022898	regulation of transmembrane transporter activity
GO:0032148	activation of protein kinase B activity
GO:0032270	positive regulation of cellular protein metabolic process
GO:0032460	negative regulation of protein oligomerization
GO:0032880	regulation of protein localization
GO:0033861	negative regulation of NAD(P)H oxidase activity
GO:0042060	wound healing
GO:0042177	negative regulation of protein catabolic process
GO:0042593	glucose homeostasis
GO:0043410	positive regulation of MAPK cascade
GO:0045725	positive regulation of glycogen biosynthetic process
GO:0045740	positive regulation of DNA replication
GO:0045818	negative regulation of glycogen catabolic process
GO:0045821	positive regulation of glycolytic process
GO:0045840	positive regulation of mitosis
GO:0045861	negative regulation of proteolysis
GO:0045922	negative regulation of fatty acid metabolic process
GO:0046326	positive regulation of glucose import
GO:0046628	positive regulation of insulin receptor signaling pathway
GO:0046631	alpha-beta T cell activation
GO:0050708	regulation of protein secretion
GO:0050709	negative regulation of protein secretion
GO:0050715	positive regulation of cytokine secretion
GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation
GO:0051092	positive regulation of NF-kappaB transcription factor activity
GO:0051897	positive regulation of protein kinase B signaling
GO:0055089	fatty acid homeostasis
GO:0060266	negative regulation of respiratory burst involved in inflammatory response
GO:0060267	positive regulation of respiratory burst
GO:2000252	negative regulation of feeding behavior

Cellular Component

GO:0005576	extracellular region
GO:0005615	extracellular space

Orthologs

No orthologs found for this gene

Cross-References

SwissProt

TrEMBL

A5PJB2 I7CLV3

UniProt Splice Variant

Entrez Gene

280829

UniGene

RefSeq

NM_001185126 NM_173926 XM_005227269

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

BC142034 DAAA02063736 EU518675 JX041514

GenPept

AAI42035 ACD35246 AFO70114

RNA Seq Atlas

280829