Version 5.4
Bos taurus Gene: EXTL1
Summary
InnateDB Gene IDBG-645242.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EXTL1
Gene Name exostosin-like 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006349
Encoded Proteins
IDBP-697935
exostosin-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158008:
This gene is a member of the multiple exostoses (EXT) family of glycosyltransferases, which function in the chain polymerization of heparan sulfate and heparin. The encoded protein harbors alpha 1,4- N-acetylglucosaminyltransferase activity, and is involved in chain elongation of heparan sulfate and possibly heparin. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:127647571-127665188
Strand Reverse strand
Band
Transcripts
ENSBTAT00000008330 ENSBTAP00000008330
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016758 transferase activity, transferring hexosyl groups
Biological Process
GO:0006486 protein glycosylation
Cellular Component
GO:0016021 integral component of membrane
GO:0031227 intrinsic component of endoplasmic reticulum membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000158008
View Gene Order
ENSMUSG00000028838
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa00534
Glycosaminoglycan biosynthesis pathway
mmu00534
Glycosaminoglycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A6QR03
UniProt Splice Variant
Entrez Gene 511060
UniGene Bt.25895
RefSeq NM_001100337
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC150061 DAAA02006380 DAAA02006381
GenPept AAI50062
RNA Seq Atlas 511060

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca