Version 5.4
| Bos taurus Gene: CATD | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Summary | |||||||||
| InnateDB Gene | IDBG-645332.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | CATD | ||||||||
| Gene Name | cathepsin D precursor | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000007622 | ||||||||
| Encoded Proteins |
cathepsin D
|
||||||||
| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| InnateDB Annotation from Orthologs | |||||||||
| Summary |
[Homo sapiens] Cathepsins: key modulators of cell death and inflammatory responses
|
||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000117984:
This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq, Jul 2008] |
||||||||
| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 29:50352064-50361497 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
|
||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 18 interaction(s) predicted by orthology.
|
||||||||
| Gene Ontology | |||||||||
Molecular Function |
|
||||||||
| Biological Process |
|
||||||||
| Cellular Component |
|
||||||||
| Orthologs | |||||||||
|
Species
Homo sapiens
Mus musculus
|
Gene ID
Gene Order
|
||||||||
| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
Prolactin pathway
|
||||||||
| REACTOME |
MHC class II antigen presentation pathway
Metabolism of Angiotensinogen to Angiotensins pathway
Collagen degradation pathway
Extracellular matrix organization pathway
Degradation of the extracellular matrix pathway
Metabolism of proteins pathway
Adaptive Immune System pathway
Immune System pathway
Peptide hormone metabolism pathway
Immune System pathway
Extracellular matrix organization pathway
MHC class II antigen presentation pathway
Adaptive Immune System pathway
Degradation of the extracellular matrix pathway
Collagen degradation pathway
|
||||||||
| KEGG |
Lysosome pathway
Lysosome pathway
|
||||||||
| INOH | |||||||||
| PID NCI |
Ceramide signaling pathway
Validated nuclear estrogen receptor alpha network
Direct p53 effectors
LKB1 signaling events
|
||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Bt.20121 | ||||||||
| RefSeq | NM_001166521 XM_005227296 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||