Version 5.4
Bos taurus Gene: GRHL3
Summary
InnateDB Gene IDBG-645351.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GRHL3
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019791
Encoded Proteins
IDBP-698064
grainyhead-like 3 (Drosophila)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000158055:
This gene encodes a member of the grainyhead family of transcription factors. The encoded protein may function as a transcription factor during development, and has been shown to stimulate migration of endothelial cells. Multiple transcript variants encoding distinct isoforms have been identified for this gene.[provided by RefSeq, Aug 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:129160819-129183500
Strand Reverse strand
Band
Transcripts
ENSBTAT00000026370 ENSBTAP00000026370
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0001736 establishment of planar polarity
GO:0006366 transcription from RNA polymerase II promoter
GO:0007389 pattern specification process
GO:0007398 ectoderm development
GO:0007417 central nervous system development
GO:0008544 epidermis development
GO:0010628 positive regulation of gene expression
GO:0032321 positive regulation of Rho GTPase activity
GO:0032956 regulation of actin cytoskeleton organization
GO:0042060 wound healing
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0061029 eyelid development in camera-type eye
GO:0090103 cochlea morphogenesis
GO:0090179 planar cell polarity pathway involved in neural tube closure
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000158055
View Gene Order
ENSMUSG00000037188
View Gene Order
Cross-References
SwissProt
TrEMBL F1N451
UniProt Splice Variant
Entrez Gene 531906
UniGene
RefSeq XM_002685773 XM_610410
HUGO HGNC:25839
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02006410
GenPept
RNA Seq Atlas 531906

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca