Version 5.4
Bos taurus Gene: DPP8
Summary
InnateDB Gene IDBG-645373.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DPP8
Gene Name dipeptidyl peptidase 8
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014807
Encoded Proteins
IDBP-698077
dipeptidyl-peptidase 8
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000074603:
This gene encodes a member of the peptidase S9B family, a small family of dipeptidyl peptidases that are able to cleave peptide substrates at a prolyl bond. The encoded protein shares similarity with dipeptidyl peptidase IV in that it is ubiquitously expressed, and hydrolyzes the same substrates. These similarities suggest that, like dipeptidyl peptidase IV, this protein may play a role in T-cell activation and immune function. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:12321152-12369941
Strand Reverse strand
Band
Transcripts
ENSBTAT00000019706 ENSBTAP00000019706
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000074603
View Gene Order
ENSMUSG00000032393
View Gene Order
Cross-References
SwissProt
TrEMBL F1N1L4
UniProt Splice Variant
Entrez Gene 536604
UniGene Bt.105529
RefSeq NM_001193231 XM_005211351 XM_005211352 XM_005211353
HUGO HGNC:16490
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02027870
GenPept
RNA Seq Atlas 536604

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca