Bos taurus Gene: FUSIP1
Summary
InnateDB Gene IDBG-645389.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FUSIP1
Gene Name splicing factor, arginine/serine-rich 13A
Synonyms FUSIP1
Species Bos taurus
Ensembl Gene ENSBTAG00000008072
Encoded Proteins
splicing factor, arginine/serine-rich 13A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000188529:
This gene product is a member of the serine-arginine (SR) family of proteins, which is involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein can influence splice site selection of adenovirus E1A pre-mRNA. It interacts with the oncoprotein TLS, and abrogates the influence of TLS on E1A pre-mRNA splicing. This gene has multiple pseudogenes. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. In addition, transcript variants utilizing alternative polyA sites exist.[provided by RefSeq, Jul 2010]
This gene product is a member of the serine-arginine (SR) family of proteins, which are involved in constitutive and regulated RNA splicing. Members of this family are characterized by N-terminal RNP1 and RNP2 motifs, which are required for binding to RNA, and multiple C-terminal SR/RS repeats, which are important in mediating association with other cellular proteins. This protein interacts with the oncoprotein TLS, and abrogates the influence of TLS on adenovirus E1A pre-mRNA splicing. This gene has pseudogenes on chromosomes 4, 9, 14, 18, and 20. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:129522680-129534734
Strand Forward strand
Band
Transcripts
ENSBTAT00000010616 ENSBTAP00000010616
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 41 interaction(s) predicted by orthology.
Predicted by orthology
Total 41 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0005515 protein binding
GO:0044822 poly(A) RNA binding
Biological Process
GO:0000375 RNA splicing, via transesterification reactions
GO:0000398 mRNA splicing, via spliceosome
GO:0006376 mRNA splice site selection
GO:0016482 cytoplasmic transport
GO:0048025 negative regulation of mRNA splicing, via spliceosome
Cellular Component
GO:0005654 nucleoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
Spliceosome pathway
Spliceosome pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q3ZBU5
UniProt Splice Variant
Entrez Gene 768310
UniGene Bt.49361 Bt.68652
RefSeq NM_001078126 XM_005203273
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103100 DAAA02006422
GenPept AAI03101
RNA Seq Atlas 768310