InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.49731

Summary

InnateDB Gene

IDBG-645428.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.49731

Gene Name

carbonic anhydrase 2

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000017733

Encoded Proteins

IDBP-698130

carbonic anhydrase 2

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000104267:
CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is one of several isozymes of carbonic anhydrase, which catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 14:79372712-79388600

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000023581

ENSBTAP00000023581

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004089	carbonate dehydratase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0046872	metal ion binding

Biological Process

GO:0002009	morphogenesis of an epithelium
GO:0006730	one-carbon metabolic process
GO:0032230	positive regulation of synaptic transmission, GABAergic
GO:0032849	positive regulation of cellular pH reduction
GO:0038166	angiotensin-activated signaling pathway
GO:0044070	regulation of anion transport
GO:0046903	secretion
GO:0051453	regulation of intracellular pH
GO:2001150	positive regulation of dipeptide transmembrane transport
GO:2001225	regulation of chloride transport

Cellular Component

GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0043209	myelin sheath
GO:0045177	apical part of cell
GO:0070062	extracellular vesicular exosome