Bos taurus Gene: TKT
Summary
InnateDB Gene IDBG-645445.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TKT
Gene Name transketolase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003758
Encoded Proteins
transketolase
transketolase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163931:
This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:48264511-48288061
Strand Forward strand
Band
Transcripts
ENSBTAT00000004892 ENSBTAP00000004892
ENSBTAT00000052142 ENSBTAP00000053095
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.
Predicted by orthology
Total 37 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004802 transketolase activity
GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0016740 transferase activity
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
GO:0048037 cofactor binding
Biological Process
GO:0008152 metabolic process
GO:0040008 regulation of growth
GO:0046166 glyceraldehyde-3-phosphate biosynthetic process
Cellular Component
GO:0005634 nucleus
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
EGFR1 pathway
REACTOME
Pentose phosphate pathway (hexose monophosphate shunt) pathway
Insulin effects increased synthesis of Xylulose-5-Phosphate pathway
Integration of energy metabolism pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
Metabolism pathway
Disease pathway
Glycogen storage diseases pathway
Insulin effects increased synthesis of Xylulose-5-Phosphate pathway
Disease pathway
Integration of energy metabolism pathway
Metabolism pathway
Pentose phosphate pathway (hexose monophosphate shunt) pathway
Glycogen storage diseases pathway
Myoclonic epilepsy of Lafora pathway
Metabolism of carbohydrates pathway
KEGG
Pentose phosphate pathway pathway
Pentose phosphate pathway pathway
INOH
Pentose phosphate cycle pathway
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.4750
RefSeq NM_001003906
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas