Version 5.4
Bos taurus Gene: PRTN3
Summary
InnateDB Gene IDBG-645521.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PRTN3
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000046105
Encoded Proteins
IDBP-698229
proteinase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 24129891
[Homo sapiens] IL32 interacts with PRTN2 (PR3) and F2RL1, triggering the PAR2-TRIF signalling axis, and IL32 may have a potential role in the transition from innate to adaptive immunity.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000196415:
Gene Information
Type Protein coding
Genomic Location Chromosome 7:44981793-44984484
Strand Forward strand
Band
Transcripts
ENSBTAT00000064845 ENSBTAP00000054275
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
GO:0019899 enzyme binding
Biological Process
GO:0006508 proteolysis
GO:0050765 negative regulation of phagocytosis
GO:0097029 mature dendritic cell differentiation
Cellular Component
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000196415
View Gene Order
ENSMUSG00000057729
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
PID NCI
cmyb_pathway
C-MYB transcription factor network
Cross-References
SwissProt
TrEMBL G3MXK8
UniProt Splice Variant
Entrez Gene 100298591
UniGene Bt.96739
RefSeq XM_002689143 XM_003585066
HUGO HGNC:9495
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02020231
GenPept
RNA Seq Atlas 100298591
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca