Bos taurus Gene: GDF9
Summary
InnateDB Gene IDBG-645713.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GDF9
Gene Name Growth/differentiation factor 9
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009478
Encoded Proteins
Growth/differentiation factor 9
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164404:
Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. Growth differentiation factor-9 (GDF9) is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9 is a member of the transforming growth factor-beta superfamily. [provided by RefSeq, Jul 2008]
This gene encodes a member of the transforming growth factor-beta superfamily. The encoded preproprotein is processed into a secreted factor that is required for ovarian folliculogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:46064180-46067119
Strand Reverse strand
Band
Transcripts
ENSBTAT00000012476 ENSBTAP00000012476
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 33 interaction(s) predicted by orthology.
Predicted by orthology
Total 33 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0008083 growth factor activity
Biological Process
GO:0001555 oocyte growth
GO:0008284 positive regulation of cell proliferation
GO:0030308 negative regulation of cell growth
GO:2000870 regulation of progesterone secretion
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
INOH
GPCR signaling pathway
TGF-beta signaling pathway
BMP2 signaling pathway
GPCR signaling pathway
BMP2 signaling pathway
TGF-beta signaling pathway
PID NCI
Cross-References
SwissProt Q9GK68
TrEMBL D0EZ62 Q95KK9
UniProt Splice Variant
Entrez Gene 282574
UniGene Bt.7047
RefSeq NM_174681
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB058416 AF307092 AJ302697 GQ922451
GenPept AAG38106 ACX50985 BAB39768 CAC39109
RNA Seq Atlas 282574