InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: PAX7

Summary

InnateDB Gene

IDBG-645775.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PAX7

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000014967

Encoded Proteins

IDBP-698526

Uncharacterized protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000009709:
This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 2:134512629-134616219

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000019924

ENSBTAP00000019924

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.

Predicted by orthology
Total	12 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000983	RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0043565	sequence-specific DNA binding

Biological Process

GO:0006338	chromatin remodeling
GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0007275	multicellular organismal development
GO:0007519	skeletal muscle tissue development
GO:0010453	regulation of cell fate commitment
GO:0010468	regulation of gene expression
GO:0014813	satellite cell commitment
GO:0021527	spinal cord association neuron differentiation
GO:0021904	dorsal/ventral neural tube patterning
GO:0031062	positive regulation of histone methylation
GO:0043393	regulation of protein binding
GO:0043403	skeletal muscle tissue regeneration
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048663	neuron fate commitment
GO:0048706	embryonic skeletal system development
GO:0051216	cartilage development
GO:0060415	muscle tissue morphogenesis
GO:2000288	positive regulation of myoblast proliferation

Cellular Component

GO:0005634

nucleus

Orthologs

Species

Homo sapiens

Mus musculus

Gene ID

Gene Order

ENSG00000009709

View Gene Order

ENSMUSG00000028736

View Gene Order

Cross-References

SwissProt

TrEMBL

E1BKL5 R4HHE4 R4HHE8 R4HHH9

UniProt Splice Variant

Entrez Gene

536229

UniGene

RefSeq

XM_002685738 XM_005197648 XM_005203360 XM_616352

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

DAAA02006543 DAAA02006544 DAAA02006545 DAAA02006546 DAAA02006547 HM804489 HM804490 HM804491 HM804492 HM804493 HM804494 HM804495 HM804496

GenPept

AEK12232 AEK12233 AEK12234 AEK12235 AEK12236 AEK12237 AEK12238 AEK12239

RNA Seq Atlas

536229