Version 5.4
| Bos taurus Gene: COL7A1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-646118.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | COL7A1 | ||||||||
| Gene Name | Uncharacterized protein | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000019081 | ||||||||
| Encoded Proteins |
collagen, type VII, alpha 1
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000114270:
This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 22:51859652-51889946 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 14 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Integrin cell surface interactions pathway
Anchoring fibril formation pathway
Assembly of collagen fibrils and other multimeric structures pathway
Collagen biosynthesis and modifying enzymes pathway
Collagen degradation pathway
Extracellular matrix organization pathway
Degradation of the extracellular matrix pathway
Laminin interactions pathway
Collagen formation pathway
Collagen formation pathway
Assembly of collagen fibrils and other multimeric structures pathway
Collagen biosynthesis and modifying enzymes pathway
Anchoring fibril formation pathway
Extracellular matrix organization pathway
Laminin interactions pathway
Integrin cell surface interactions pathway
Degradation of the extracellular matrix pathway
Collagen degradation pathway
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| KEGG |
Protein digestion and absorption pathway
Protein digestion and absorption pathway
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| INOH |
Integrin signaling pathway pathway
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| PID NCI |
Beta1 integrin cell surface interactions
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | E1B7H2 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 507133 | ||||||||
| UniGene | Bt.12599 | ||||||||
| RefSeq | XM_002697051 XM_002702778 | ||||||||
| HUGO | HGNC:2214 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02054431 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 507133 | ||||||||