InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SMARCC1

Summary

InnateDB Gene

IDBG-646186.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SMARCC1

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000031567

Encoded Proteins

IDBP-698974

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1

IDBP-698975

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173473:
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 22:52521861-52619906

Strand

Forward strand

Band

Transcripts

ENSBTAT00000044741	ENSBTAP00000042212
ENSBTAT00000065210	ENSBTAP00000055336

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 107 interaction(s) predicted by orthology.

Predicted by orthology
Total	107 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000978	RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980	RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0005515	protein binding
GO:0031492	nucleosomal DNA binding
GO:0047485	protein N-terminus binding

Biological Process

GO:0006337	nucleosome disassembly
GO:0006338	chromatin remodeling
GO:0008286	insulin receptor signaling pathway
GO:0009887	organ morphogenesis
GO:0043044	ATP-dependent chromatin remodeling
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter

Cellular Component

GO:0000790	nuclear chromatin
GO:0001741	XY body
GO:0005622	intracellular
GO:0005634	nucleus
GO:0016514	SWI/SNF complex
GO:0043234	protein complex
GO:0071564	npBAF complex
GO:0071565	nBAF complex