Bos taurus Gene: PLCB2
Summary
InnateDB Gene IDBG-646214.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLCB2
Gene Name 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019079
Encoded Proteins
phospholipase C, beta 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137841:
Gene Information
Type Protein coding
Genomic Location Chromosome 10:36024408-36044688
Strand Reverse strand
Band
Transcripts
ENSBTAT00000025402 ENSBTAP00000025402
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004435 phosphatidylinositol phospholipase C activity
GO:0004629 phospholipase C activity
GO:0004871 signal transducer activity
GO:0005509 calcium ion binding
GO:0005515 protein binding
GO:0008081 phosphoric diester hydrolase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006629 lipid metabolic process
GO:0007165 signal transduction
GO:0016042 lipid catabolic process
GO:0035556 intracellular signal transduction
GO:0050913 sensory perception of bitter taste
Cellular Component
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
G alpha (q) signalling events pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
G beta:gamma signalling through PLC beta pathway
PLC beta mediated events pathway
Opioid Signalling pathway
Presynaptic function of Kainate receptors pathway
Synthesis of IP3 and IP4 in the cytosol pathway
Acetylcholine regulates insulin secretion pathway
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion pathway
Regulation of insulin secretion pathway
Integration of energy metabolism pathway
Ca2+ pathway pathway
beta-catenin independent WNT signaling pathway
Signaling by Wnt pathway
Neuronal System pathway
Signaling by GPCR pathway
G-protein beta:gamma signalling pathway
Signal Transduction pathway
GPCR downstream signaling pathway
G-protein mediated events pathway
Activation of Kainate Receptors upon glutamate binding pathway
Free fatty acids regulate insulin secretion pathway
Transmission across Chemical Synapses pathway
Inositol phosphate metabolism pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Metabolism pathway
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion pathway
GPCR downstream signaling pathway
Signaling by Wnt pathway
Signaling by GPCR pathway
Integration of energy metabolism pathway
G beta:gamma signalling through PLC beta pathway
Activation of Kainate Receptors upon glutamate binding pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Gastrin-CREB signalling pathway via PKC and MAPK pathway
Acetylcholine regulates insulin secretion pathway
beta-catenin independent WNT signaling pathway
Metabolism pathway
Regulation of insulin secretion pathway
Ca2+ pathway pathway
Neuronal System pathway
G alpha (q) signalling events pathway
Opioid Signalling pathway
Presynaptic function of Kainate receptors pathway
G-protein beta:gamma signalling pathway
Signal Transduction pathway
Inositol phosphate metabolism pathway
Synthesis of IP3 and IP4 in the cytosol pathway
Free fatty acids regulate insulin secretion pathway
Transmission across Chemical Synapses pathway
PLC beta mediated events pathway
G-protein mediated events pathway
KEGG
GnRH signaling pathway pathway
Gap junction pathway
Wnt signaling pathway pathway
Inositol phosphate metabolism pathway
Long-term potentiation pathway
Alzheimer's disease pathway
Phosphatidylinositol signaling system pathway
Taste transduction pathway
Long-term depression pathway
Calcium signaling pathway pathway
Melanogenesis pathway
Vascular smooth muscle contraction pathway
Chemokine signaling pathway pathway
Huntington's disease pathway
Gastric acid secretion pathway
Amoebiasis pathway
Chagas disease (American trypanosomiasis) pathway
Pancreatic secretion pathway
Salivary secretion pathway
African trypanosomiasis pathway
Carbohydrate digestion and absorption pathway
Taste transduction pathway
Calcium signaling pathway pathway
Alzheimer's disease pathway
Melanogenesis pathway
Wnt signaling pathway pathway
Gap junction pathway
Phosphatidylinositol signaling system pathway
GnRH signaling pathway pathway
Long-term potentiation pathway
Long-term depression pathway
Inositol phosphate metabolism pathway
Chemokine signaling pathway pathway
Vascular smooth muscle contraction pathway
Huntington's disease pathway
Amoebiasis pathway
Gastric acid secretion pathway
Carbohydrate digestion and absorption pathway
Salivary secretion pathway
Pancreatic secretion pathway
Chagas disease (American trypanosomiasis) pathway
African trypanosomiasis pathway
INOH
GPCR GroupI metabotropic glutamate receptor signaling pathway pathway
GPCR signaling pathway
Inositol phosphate metabolism pathway
PID NCI
Alpha-synuclein signaling
Thromboxane A2 receptor signaling
S1P1 pathway
IL8- and CXCR2-mediated signaling events
IL8- and CXCR1-mediated signaling events
RAC1 signaling pathway
PAR4-mediated thrombin signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas