Version 5.4
Bos taurus Gene: FYCO1
Summary
InnateDB Gene IDBG-646253.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FYCO1
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015698
Encoded Proteins
IDBP-699042
FYVE and coiled-coil domain containing 1
IDBP-699043
FYVE and coiled-coil domain containing 1
IDBP-699045
FYVE and coiled-coil domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163820:
This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2). [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:53951029-54026241
Strand Forward strand
Band
Transcripts
ENSBTAT00000063071 ENSBTAP00000055120
ENSBTAT00000020845 ENSBTAP00000020845
ENSBTAT00000065084 ENSBTAP00000056152
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 21 interaction(s) predicted by orthology.
Predicted by orthology
Total 21 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006810 transport
GO:0072383 plus-end-directed vesicle transport along microtubule
Cellular Component
GO:0005764 lysosome
GO:0005770 late endosome
GO:0005776 autophagic vacuole
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000163820
View Gene Order
ENSMUSG00000025241
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.21979
RefSeq XM_001790527 XM_002697098 XM_005196494 XM_005196495 XM_005196496 XM_005196497 XM_005196499 XM_005223112 XM_005223113 XM_005223114 XM_005223115
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca