Version 5.4
Mus musculus Gene: Fyco1
Summary
InnateDB Gene IDBG-206471.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Fyco1
Gene Name FYVE and coiled-coil domain containing 1
Synonyms 2810409M01Rik; Mem2; RUFY3; ZFYVE7
Species Mus musculus
Ensembl Gene ENSMUSG00000025241
Encoded Proteins
IDBP-206473
FYVE and coiled-coil domain containing 1
IDBP-622372
FYVE and coiled-coil domain containing 1
IDBP-790487
FYVE and coiled-coil domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000163820:
This gene encodes a protein that contains a RUN domain, FYVE-type zinc finger domain and Golgi dynamics (GOLD) domain. The encoded protein plays a role in microtubule plus end-directed transport of autophagic vesicles through interactions with the small GTPase Rab7, phosphatidylinositol-3-phosphate (PI3P) and the autophagosome marker LC3. Mutations in this gene are a cause of autosomal recessive congenital cataract-2 (CATC2). [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:123789510-123851899
Strand Reverse strand
Band F4
Transcripts
ENSMUST00000084715 ENSMUSP00000081764
ENSMUST00000167595 ENSMUSP00000133222
ENSMUST00000184082 ENSMUSP00000139343
ENSMUST00000183700
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006810 transport
GO:0072383 plus-end-directed vesicle transport along microtubule
Cellular Component
GO:0005764 lysosome
GO:0005770 late endosome
GO:0005776 autophagic vacuole
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0031410 cytoplasmic vesicle
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000163820
View Gene Order
ENSBTAG00000015698
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.252941 Mm.401205
RefSeq NM_001110253 NM_148925
OMIM
CCDS CCDS40819
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca