InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CCR9

Summary

InnateDB Gene

IDBG-646262.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CCR9

Gene Name

C-C chemokine receptor type 9

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000031348

Encoded Proteins

IDBP-699047

C-C chemokine receptor type 9

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173585:
The protein encoded by this gene is a member of the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptors are key regulators of the thymocytes migration and maturation in normal and inflammation conditions. The specific ligand of this receptor is CCL25. It has been found that this gene is differentially expressed by T lymphocytes of small intestine and colon, suggested a role in the thymocytes recruitment and development that may permit functional specialization of immune responses in different segment of the gastrointestinal tract. This gene is mapped to the chemokine receptor gene cluster region. Two alternatively spliced transcript variants have been described. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 22:54041058-54057181

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000044420

ENSBTAP00000041919

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0004950	chemokine receptor activity
GO:0005515	protein binding
GO:0016493	C-C chemokine receptor activity

Biological Process

GO:0006935	chemotaxis
GO:0006955	immune response
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0070098	chemokine-mediated signaling pathway