Version 5.4
Bos taurus Gene: SLC36A2
Summary
InnateDB Gene IDBG-646336.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC36A2
Gene Name proton-coupled amino acid transporter 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020809
Encoded Proteins
IDBP-699130
solute carrier family 36 (proton/amino acid symporter), member 2
IDBP-699131
solute carrier family 36 (proton/amino acid symporter), member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000186335:
This gene encodes a pH-dependent proton-coupled amino acid transporter that belongs to the amino acid auxin permease 1 protein family. The encoded protein primarily transports small amino acids such as glycine, alanine and proline. Mutations in this gene are associated with iminoglycinuria and hyperglycinuria. [provided by RefSeq, Sep 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:64561459-64587897
Strand Reverse strand
Band
Transcripts
ENSBTAT00000027731 ENSBTAP00000027731
ENSBTAT00000065288 ENSBTAP00000056114
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005280 hydrogen:amino acid symporter activity
GO:0015180 L-alanine transmembrane transporter activity
GO:0015187 glycine transmembrane transporter activity
GO:0015193 L-proline transmembrane transporter activity
Biological Process
GO:0015808 L-alanine transport
GO:0015816 glycine transport
GO:0015824 proline transport
GO:0015992 proton transport
GO:0035524 proline transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000186335
View Gene Order
ENSMUSG00000020264
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_19348
Proton-coupled neutral amino acid transporters pathway
REACT_13796
Amino acid transport across the plasma membrane pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_229738
Proton-coupled neutral amino acid transporters pathway
REACT_251788
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_230460
Amino acid transport across the plasma membrane pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BGG5
UniProt Splice Variant
Entrez Gene 509629
UniGene Bt.61588
RefSeq NM_001206180 XM_005209639
HUGO HGNC:18762
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02020641
GenPept
RNA Seq Atlas 509629

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca