Bos taurus Gene: HAVCR2
Summary
InnateDB Gene IDBG-646380.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HAVCR2
Gene Name hepatitis A virus cellular receptor 2 precursor
Synonyms CRSP9
Species Bos taurus
Ensembl Gene ENSBTAG00000000495
Encoded Proteins
hepatitis A virus cellular receptor 2
hepatitis A virus cellular receptor 2
hepatitis A virus cellular receptor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000155868:
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 7:70824035-70870844
Strand Reverse strand
Band
Transcripts
ENSBTAT00000049360 ENSBTAP00000046261
ENSBTAT00000000626 ENSBTAP00000000626
ENSBTAT00000018133 ENSBTAP00000018133
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 40 interaction(s) predicted by orthology.
Predicted by orthology
Total 40 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0001104 RNA polymerase II transcription cofactor activity
GO:0005515 protein binding
Biological Process
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0019827 stem cell maintenance
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0005739 mitochondrion
GO:0016592 mediator complex
GO:0031965 nuclear membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
PPARA activates gene expression pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Generic Transcription Pathway pathway
Transcriptional regulation of white adipocyte differentiation pathway
Developmental Biology pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Gene Expression pathway
Transcriptional Regulation of Adipocyte Differentiation in 3T3-L1 Pre-adipocytes pathway
Transcriptional regulation of white adipocyte differentiation pathway
Mus musculus biological processes pathway
Fatty acid, triacylglycerol, and ketone body metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) pathway
Gene Expression pathway
PPARA activates gene expression pathway
Developmental Biology pathway
Generic Transcription Pathway pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.31273
RefSeq NM_001077105 NM_001079583 XM_005209670
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas