InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SEC61A1

Summary

InnateDB Gene

IDBG-646508.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SEC61A1

Gene Name

Protein transport protein Sec61 subunit alpha isoform 1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000004937

Encoded Proteins

IDBP-699321

Protein transport protein Sec61 subunit alpha isoform 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000058262:
The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 22:60217808-60229341

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000006494

ENSBTAP00000006494

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0043022	ribosome binding

Biological Process

GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0006620	posttranslational protein targeting to membrane
GO:0006810	transport
GO:0007029	endoplasmic reticulum organization
GO:0015031	protein transport
GO:0016049	cell growth
GO:0045047	protein targeting to ER

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005789	endoplasmic reticulum membrane
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0030176	integral component of endoplasmic reticulum membrane