Version 5.4
| Bos taurus Gene: LNPEP | |||||||||||
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| Summary | |||||||||||
| InnateDB Gene | IDBG-646592.3 | ||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
| Gene Symbol | LNPEP | ||||||||||
| Gene Name | Uncharacterized protein | ||||||||||
| Synonyms | |||||||||||
| Species | Bos taurus | ||||||||||
| Ensembl Gene | ENSBTAG00000019900 | ||||||||||
| Encoded Proteins |
leucyl/cystinyl aminopeptidase
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| Protein Structure | |||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||
| Entrez Gene | |||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113441:
This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||
| Type | Protein coding | ||||||||||
| Genomic Location | Chromosome 7:98825233-98878164 | ||||||||||
| Strand | Forward strand | ||||||||||
| Band | |||||||||||
| Transcripts |
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| Interactions | |||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||
| NETPATH |
TCR pathway
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| REACTOME |
Antigen processing: Ubiquitination & Proteasome degradation pathway
Endosomal/Vacuolar pathway pathway
Translocation of GLUT4 to the plasma membrane pathway
Antigen processing-Cross presentation pathway
Adaptive Immune System pathway
Immune System pathway
Class I MHC mediated antigen processing & presentation pathway
Membrane Trafficking pathway
Class I MHC mediated antigen processing & presentation pathway
Membrane Trafficking pathway
Immune System pathway
Endosomal/Vacuolar pathway pathway
Antigen processing: Ubiquitination & Proteasome degradation pathway
Antigen processing-Cross presentation pathway
Adaptive Immune System pathway
Translocation of GLUT4 to the plasma membrane pathway
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| KEGG |
Renin-angiotensin system pathway
Renin-angiotensin system pathway
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| INOH | |||||||||||
| PID NCI |
Insulin-mediated glucose transport
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| Cross-References | |||||||||||
| SwissProt | |||||||||||
| TrEMBL | |||||||||||
| UniProt Splice Variant | |||||||||||
| Entrez Gene | |||||||||||
| UniGene | Bt.94750 | ||||||||||
| RefSeq | XM_002689410 XM_599899 | ||||||||||
| HUGO | |||||||||||
| OMIM | |||||||||||
| CCDS | |||||||||||
| HPRD | |||||||||||
| IMGT | |||||||||||
| EMBL | |||||||||||
| GenPept | |||||||||||
| RNA Seq Atlas | |||||||||||