Version 5.4
Bos taurus Gene: SEL1L
Summary
InnateDB Gene IDBG-646912.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SEL1L
Gene Name protein sel-1 homolog 1 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008083
Encoded Proteins
IDBP-699761
sel-1 suppressor of lin-12-like (C. elegans)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000071537:
The protein encoded by this gene is part of a protein complex required for the retrotranslocation or dislocation of misfolded proteins from the endoplasmic reticulum lumen to the cytosol, where they are degraded by the proteasome in a ubiquitin-dependent manner. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:93904711-93965166
Strand Reverse strand
Band
Transcripts
ENSBTAT00000010628 ENSBTAP00000010628
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 25 interaction(s) predicted by orthology.
Predicted by orthology
Total 25 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0034976 response to endoplasmic reticulum stress
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000071537
View Gene Order
ENSMUSG00000020964
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_118798
Pre-NOTCH Processing in Golgi pathway
REACT_228190
Processing-defective Hh variants abrogate ligand secretion pathway
REACT_228134
Signaling by Hedgehog pathway
REACT_118744
Pre-NOTCH Expression and Processing pathway
REACT_111102
Signal Transduction pathway
REACT_228209
Hh ligand biogenesis disease pathway
REACT_228111
Hedgehog ligand biogenesis pathway
REACT_299
Signaling by NOTCH pathway
REACT_116125
Disease pathway
REACT_189085
Disease pathway
REACT_233316
Hedgehog ligand biogenesis pathway
REACT_248271
Processing-defective Hh variants abrogate ligand secretion pathway
REACT_196494
Pre-NOTCH Expression and Processing pathway
REACT_232469
Hh ligand biogenesis disease pathway
REACT_196517
Pre-NOTCH Processing in Golgi pathway
REACT_250064
Signaling by Hedgehog pathway
REACT_188257
Signal Transduction pathway
REACT_231152
Signaling by NOTCH pathway
KEGG
hsa04141
Protein processing in endoplasmic reticulum pathway
mmu04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Bt.10262
RefSeq NM_001206908
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca