Version 5.4
Bos taurus Gene: GP9
Summary
InnateDB Gene IDBG-647817.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GP9
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000014666
Encoded Proteins
IDBP-700607
glycoprotein IX (platelet)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000169704:
This gene encodes a small membrane glycoprotein found on the surface of human platelets. It forms a 1-to-1 noncovalent complex with glycoprotein Ib, a platelet surface membrane glycoprotein complex that functions as a receptor for von Willebrand factor. The complete receptor complex includes noncovalent association of the alpha and beta subunits with the protein encoded by this gene and platelet glycoprotein V. Defects in this gene are a cause of Bernard-Soulier syndrome, also known as giant platelet disease. These patients have unusually large platelets and have a clinical bleeding tendency. [provided by RefSeq, Oct 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 22:59687612-59688166
Strand Forward strand
Band
Transcripts
ENSBTAT00000019525 ENSBTAP00000019525
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000169704
View Gene Order
ENSMUSG00000030054
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_1230
Platelet Adhesion to exposed collagen pathway
REACT_326
Intrinsic Pathway pathway
REACT_23847
GP1b-IX-V activation signalling pathway
REACT_278
Platelet Aggregation (Plug Formation) pathway
REACT_2051
Formation of Fibrin Clot (Clotting Cascade) pathway
REACT_798
Platelet activation, signaling and aggregation pathway
REACT_604
Hemostasis pathway
REACT_245546
GP1b-IX-V activation signalling pathway
REACT_224553
Hemostasis pathway
REACT_224879
Platelet activation, signaling and aggregation pathway
REACT_239392
Intrinsic Pathway pathway
REACT_235097
Formation of Fibrin Clot (Clotting Cascade) pathway
REACT_225107
Platelet Adhesion to exposed collagen pathway
REACT_249309
Platelet Aggregation (Plug Formation) pathway
KEGG
hsa04640
Hematopoietic cell lineage pathway
hsa04512
ECM-receptor interaction pathway
mmu04512
ECM-receptor interaction pathway
mmu04640
Hematopoietic cell lineage pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1N1G4
UniProt Splice Variant
Entrez Gene 617668
UniGene
RefSeq XM_005196522 XM_005223180
HUGO HGNC:4444
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02054665
GenPept
RNA Seq Atlas 617668

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca