InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: HRH2

Summary

InnateDB Gene

IDBG-647824.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HRH2

Gene Name

Uncharacterized protein

Synonyms

HRH2

Species

Bos taurus

Ensembl Gene

ENSBTAG00000044071

Encoded Proteins

IDBP-700614

Uncharacterized protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000113749:
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 10:5409681-5410760

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000061359

ENSBTAP00000053816

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity
GO:0004969	histamine receptor activity

Biological Process

GO:0001696	gastric acid secretion
GO:0001697	histamine-induced gastric acid secretion
GO:0001698	gastrin-induced gastric acid secretion
GO:0003382	epithelial cell morphogenesis
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007613	memory
GO:0008542	visual learning
GO:0045907	positive regulation of vasoconstriction
GO:0048167	regulation of synaptic plasticity
GO:0048565	digestive tract development
GO:0048732	gland development