Version 5.4
| Bos taurus Gene: CH25H | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-648811.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | CH25H | ||||||||
| Gene Name | cholesterol 25-hydroxylase | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000011115 | ||||||||
| Encoded Proteins |
cholesterol 25-hydroxylase
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000138135:
This is an intronless gene that is involved in cholesterol and lipid metabolism. The encoded protein is a membrane protein and contains clusters of histidine residues essential for catalytic activity. Unlike most other sterol hydroxylases, this enzyme is a member of a small family of enzymes that utilize diiron cofactors to catalyze the hydroxylation of hydrophobic substrates. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 26:10976195-10978251 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Synthesis of bile acids and bile salts pathway
Metabolism of lipids and lipoproteins pathway
Bile acid and bile salt metabolism pathway
Metabolism pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Synthesis of bile acids and bile salts pathway
Bile acid and bile salt metabolism pathway
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| KEGG |
Primary bile acid biosynthesis pathway
Primary bile acid biosynthesis pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | Q0P599 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 506132 | ||||||||
| UniGene | Bt.70866 Bt.91113 | ||||||||
| RefSeq | NM_001075243 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | BC120312 DAAA02058733 | ||||||||
| GenPept | AAI20313 | ||||||||
| RNA Seq Atlas | 506132 | ||||||||