Version 5.4
| Bos taurus Gene: IFIT2 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-648812.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | IFIT2 | ||||||||
| Gene Name | Uncharacterized protein | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000034918 | ||||||||
| Encoded Proteins |
interferon-induced protein with tetratricopeptide repeats 2
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| InnateDB Annotation from Orthologs | |||||||||
| Summary |
[Homo sapiens] IFIT2 belongs to type 1 interferon response genes and is highly induced after stimulation with LPS and selectively affects LPS induced protein expression by regulation at different post-transcriptional levels.
[Homo sapiens] IFIT2 expression imparts anti-viral immunity to restrict West Nile virus infection and control viral pathogenesis. (Demonstrated in mice)
[Mus musculus] Ifit2 expression imparts anti-viral immunity to restrict West Nile virus infection and control viral pathogenesis.
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| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000119922:
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 26:11069934-11071316 | ||||||||
| Strand | Forward strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 37 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH | |||||||||
| REACTOME |
Interferon alpha/beta signaling pathway
Cytokine Signaling in Immune system pathway
Interferon Signaling pathway
Immune System pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | F1MQW8 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 527528 | ||||||||
| UniGene | Bt.24795 | ||||||||
| RefSeq | XM_001787823 XM_002698356 | ||||||||
| HUGO | HGNC:5409 | ||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | DAAA02058733 | ||||||||
| GenPept | |||||||||
| RNA Seq Atlas | 527528 | ||||||||