Bos taurus Gene: HIST2H2AB
Summary
InnateDB Gene IDBG-649027.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HIST2H2AB
Gene Name Histone H2A
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000038476
Encoded Proteins
Histone H2A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000184270:
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:20770059-20770469
Strand Forward strand
Band
Transcripts
ENSBTAT00000045062 ENSBTAP00000042479
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 12 interaction(s) predicted by orthology.
Predicted by orthology
Total 12 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0043565 sequence-specific DNA binding
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006334 nucleosome assembly
Cellular Component
GO:0000786 nucleosome
GO:0005622 intracellular
GO:0005634 nucleus
GO:0005694 chromosome
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
HATs acetylate histones pathway
HDACs deacetylate histones pathway
Chromatin organization pathway
RMTs methylate histone arginines pathway
Chromatin modifying enzymes pathway
Meiotic Recombination pathway
Meiotic Synapsis pathway
Mus musculus biological processes pathway
NoRC negatively regulates rRNA expression pathway
Chromatin organization pathway
HATs acetylate histones pathway
Meiotic synapsis pathway
Cell Cycle pathway
NoRC negatively regulates rRNA expression pathway
Chromatin modifying enzymes pathway
Epigenetic regulation of gene expression pathway
Gene Expression pathway
DNA methylation pathway
Negative epigenetic regulation of rRNA expression pathway
RMTs methylate histone arginines pathway
Meiosis pathway
HDACs deacetylate histones pathway
KEGG
Systemic lupus erythematosus pathway
Systemic lupus erythematosus pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BH22 Q2QJG7
UniProt Splice Variant
Entrez Gene 614974
UniGene
RefSeq XM_002686052 XM_866640
HUGO HGNC:20508
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02007273 DQ066891
GenPept AAZ32292
RNA Seq Atlas 100299831 614974