Homo sapiens Gene: SULT1C2
Summary
InnateDB Gene IDBG-64928.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SULT1C2
Gene Name sulfotransferase family, cytosolic, 1C, member 2
Synonyms humSULTC2; ST1C1; ST1C2; SULT1C1
Species Homo sapiens
Ensembl Gene ENSG00000198203
Encoded Proteins
sulfotransferase family, cytosolic, 1C, member 2
sulfotransferase family, cytosolic, 1C, member 2
sulfotransferase family, cytosolic, 1C, member 2
sulfotransferase family, cytosolic, 1C, member 2
sulfotransferase family, cytosolic, 1C, member 2
sulfotransferase family, cytosolic, 1C, member 2
sulfotransferase family, cytosolic, 1C, member 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 2:108288639-108309915
Strand Forward strand
Band q12.3
Transcripts
ENST00000326853 ENSP00000319622
ENST00000251481 ENSP00000251481
ENST00000409880 ENSP00000387054
ENST00000409067 ENSP00000387340
ENST00000437390 ENSP00000399651
ENST00000438339 ENSP00000401996
ENST00000442801 ENSP00000415194
ENST00000492554
ENST00000495441
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008146 sulfotransferase activity
Biological Process
GO:0006805 xenobiotic metabolic process
GO:0008152 metabolic process
GO:0009308 amine metabolic process
GO:0044281 small molecule metabolic process
GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process
GO:0051923 sulfation
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
Cytosolic sulfonation of small molecules pathway
Phase II conjugation pathway
Metabolism pathway
Biological oxidations pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene 6819
UniGene Hs.436123 Hs.668521
RefSeq NM_001056 NM_176825 XM_005264013
HUGO HGNC:11456
OMIM 602385
CCDS CCDS2075 CCDS2076
HPRD 03858
IMGT
EMBL
GenPept
RNA Seq Atlas 102723646 6819