Version 5.4
Homo sapiens Gene: MAP6
Summary
InnateDB Gene IDBG-64942.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAP6
Gene Name microtubule-associated protein 6
Synonyms MTAP6; N-STOP; STOP
Species Homo sapiens
Ensembl Gene ENSG00000171533
Encoded Proteins
IDBP-64944
microtubule-associated protein 6
IDBP-381184
microtubule-associated protein 6
IDBP-601537
microtubule-associated protein 6
IDBP-810308
microtubule-associated protein 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a microtubule-associated protein. The encoded protein is a calmodulin-binding and calmodulin-regulated protein that is involved in microtubule stabilization. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:75586918-75669120
Strand Reverse strand
Band q13.5
Transcripts
ENST00000304771 ENSP00000307093
ENST00000434603 ENSP00000415108
ENST00000526740 ENSP00000434278
ENST00000526689
ENST00000614044 ENSP00000484920
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005516 calmodulin binding
GO:0008017 microtubule binding
Biological Process
GO:0000226 microtubule cytoskeleton organization
GO:0006810 transport
GO:0032418 lysosome localization
GO:0048813 dendrite morphogenesis
Cellular Component
GO:0005794 Golgi apparatus
GO:0005874 microtubule
GO:0048471 perinuclear region of cytoplasm
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000055407
View Gene Order
ENSBTAG00000001028
Not yet available
Cross-References
SwissProt Q96JE9
TrEMBL
UniProt Splice Variant
Entrez Gene 4135
UniGene Hs.239444 Hs.585540 Hs.623857
RefSeq NM_033063 NM_207577
HUGO HGNC:6868
OMIM 601783
CCDS CCDS31641 CCDS44686
HPRD 15989
IMGT
EMBL AB058781 AK123340 AP001922 BC063860 BC139780 BC150254
GenPept AAH63860 AAI39781 AAI50255 BAB47507 BAC85586
RNA Seq Atlas 4135

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca