Version 5.4
Homo sapiens Gene: ACER3
Summary
InnateDB Gene IDBG-65242.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACER3
Gene Name alkaline ceramidase 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000078124
Encoded Proteins
IDBP-65244
alkaline ceramidase 3
IDBP-587383
alkaline ceramidase 3
IDBP-591699
alkaline ceramidase 3
IDBP-593592
alkaline ceramidase 3
IDBP-592541
alkaline ceramidase 3
IDBP-601082
alkaline ceramidase 3
IDBP-603741
alkaline ceramidase 3
IDBP-590186
alkaline ceramidase 3
IDBP-599138
alkaline ceramidase 3
IDBP-592152
alkaline ceramidase 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 11:76860867-77026797
Strand Forward strand
Band q13.5
Transcripts
ENST00000278544 ENSP00000278544
ENST00000534206 ENSP00000435733
ENST00000532485 ENSP00000434480
ENST00000530182
ENST00000525194 ENSP00000432109
ENST00000525861 ENSP00000432379
ENST00000531461 ENSP00000433368
ENST00000530334 ENSP00000435048
ENST00000526597 ENSP00000431149
ENST00000533873 ENSP00000436252
ENST00000531352 ENSP00000431504
ENST00000527508
ENST00000525325
ENST00000530921
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0070774 phytoceramidase activity
Biological Process
GO:0006665 sphingolipid metabolic process
GO:0006672 ceramide metabolic process
GO:0008284 positive regulation of cell proliferation
GO:0030148 sphingolipid biosynthetic process
GO:0044281 small molecule metabolic process
GO:0046512 sphingosine biosynthetic process
GO:0071602 phytosphingosine biosynthetic process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0030173 integral component of Golgi membrane
GO:0030176 integral component of endoplasmic reticulum membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000030760
View Gene Order
ENSBTAG00000017218
Not yet available
Pathways
NETPATH
REACTOME
REACT_115810
Sphingolipid de novo biosynthesis pathway
REACT_19323
Sphingolipid metabolism pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_111217
Metabolism pathway
KEGG
hsa00600
Sphingolipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.23862 Hs.606691 Hs.608049 Hs.712340 Hs.717415
RefSeq NM_001300953 NM_001300954 NM_001300955 NM_018367 XM_005274087 XM_005274089 XM_005274090
HUGO
OMIM
CCDS CCDS73352 CCDS8247
HPRD 17844
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca