Version 5.4
Homo sapiens Gene: CACNG5
Summary
InnateDB Gene IDBG-65252.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CACNG5
Gene Name calcium channel, voltage-dependent, gamma subunit 5
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000075429
Encoded Proteins
IDBP-65254
calcium channel, voltage-dependent, gamma subunit 5
IDBP-598113
calcium channel, voltage-dependent, gamma subunit 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. This gene is a susceptibility locus for schizophrenia and bipolar disorder. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 17:66835117-66885486
Strand Forward strand
Band q24.2
Transcripts
ENST00000307139 ENSP00000303092
ENST00000533854 ENSP00000436836
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005245 voltage-gated calcium channel activity
GO:0005515 protein binding
GO:0015075 ion transmembrane transporter activity
Biological Process
GO:0006810 transport
GO:0070588 calcium ion transmembrane transport
GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
Cellular Component
GO:0014069 postsynaptic density
GO:0016021 integral component of membrane
GO:0030054 cell junction
GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
GO:0045211 postsynaptic membrane
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa04010
MAPK signaling pathway pathway
hsa05412
Arrhythmogenic right ventricular cardiomyopathy (ARVC) pathway
hsa05410
Hypertrophic cardiomyopathy (HCM) pathway
hsa04260
Cardiac muscle contraction pathway
hsa05414
Dilated cardiomyopathy pathway
INOH
INOH website
GPCR Dopamine D1like receptor signaling pathway pathway
PID NCI
Cross-References
SwissProt Q9UF02
TrEMBL
UniProt Splice Variant
Entrez Gene 27091
UniGene Hs.278907
RefSeq NM_145811
HUGO HGNC:1409
OMIM 606405
CCDS CCDS11665
HPRD
IMGT
EMBL AF142618 AF142619 AF142620 AF142621 AF148220 AF361351 AF458898 AK290171 BC101607 BC101633
GenPept AAF00132 AAF03089 AAI01608 AAI01634 AAL50046 AAM00595 BAF82860
RNA Seq Atlas 27091

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca