Version 5.4
| Homo sapiens Gene: WDR45 | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-65371.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | WDR45 | ||||||||||||||||||
| Gene Name | WD repeat domain 45 | ||||||||||||||||||
| Synonyms | NBIA4; NBIA5; WDRX1; WIPI-4; WIPI4 | ||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000196998 | ||||||||||||||||||
| Encoded Proteins |
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
WD repeat domain 45
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| Protein Structure | |||||||||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome X:49074433-49101170 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | p11.23 | ||||||||||||||||||
| Transcripts | |||||||||||||||||||
| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Cross-References | |||||||||||||||||||
| SwissProt | |||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| UniGene | Hs.613710 Hs.632807 | ||||||||||||||||||
| RefSeq | NM_001029896 NM_007075 NM_007213 | ||||||||||||||||||
| HUGO | |||||||||||||||||||
| OMIM | |||||||||||||||||||
| CCDS | CCDS14318 CCDS35250 CCDS14317 | ||||||||||||||||||
| HPRD | 06597 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | |||||||||||||||||||
| GenPept | |||||||||||||||||||
| RNA Seq Atlas | |||||||||||||||||||