Version 5.4
Homo sapiens Gene: CD33
Summary
InnateDB Gene IDBG-65737.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CD33
Gene Name CD33 molecule
Synonyms p67; SIGLEC-3; SIGLEC3
Species Homo sapiens
Ensembl Gene ENSG00000105383
Encoded Proteins
IDBP-65739
CD33 molecule
IDBP-246970
CD33 molecule
IDBP-384041
CD33 molecule
IDBP-384042
CD33 molecule
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:51225064-51243860
Strand Forward strand
Band q13.41
Transcripts
ENST00000262262 ENSP00000262262
ENST00000391796 ENSP00000375673
ENST00000421133 ENSP00000410126
ENST00000436584 ENSP00000403331
ENST00000600557
ENST00000601785
ENST00000598473
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
Experimentally validated
Total 19 [view]
Protein-Protein 19 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0007155 cell adhesion
GO:0007165 signal transduction
GO:0007267 cell-cell signaling
GO:0008285 negative regulation of cell proliferation
Cellular Component
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0009897 external side of plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
No orthologs found for this gene
Pathways
NETPATH
REACTOME
KEGG
hsa04640
Hematopoietic cell lineage pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.83731
RefSeq NM_001082618 NM_001177608 NM_001772 XM_005259434
HUGO
OMIM
CCDS CCDS33084 CCDS46157 CCDS54299
HPRD 01165
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca